While they were worshiping the Lord and fasting, the Holy Spirit said, “Set apart for me Barnabas and Saul for the work to which I have called them.” – Acts 13:2 NIV
Antioch was the home of the first known, predominately Gentile church. While it is not explicitly stated here, it would appear that the church leadership is seeking direction from God as they worship and fast. I suspect that this could very well be connected with God’s earlier calling of Paul (Acts 9:15) to proclaim Christ to the Gentiles. God responds to them in some fashion, making clear that Saul (Paul) and Barnabas are to be sent off to proclaim the gospel. So they fasted, prayed, laid hands on them, and sent them off. And thus the first intentional missionaries are sent out.
While I do not expect that there are many Apostle Pauls waiting to be sent out from among us, this church at Antioch does set a good example of how to seek God’s direction. They worshipped, bowing down before their sovereign Lord; fasted, denying themselves and any outside distractions; and prayed, seeking God’s direction. And I suspect that it was not just for a few minutes on Sunday. I wonder what would happen if the church today was to do that? Or for us as individual believers?